The Best Hypoallergenic Dogs, or Tier 1 Hypoallergenic Dog Breeds, include small dogs such as the Bichon Frise, Toy Poodle, Havanese, Maltese, Chihuahua, Chinese Crested and Schnauzer, medium-sized dog breeds such as the Soft-Coated Wheaton Terrier, Portuguese Water Dog, Spanish Water Dog, Portuguese Water Dog, Xoloitzcuintle (or Mexican Hairless) and Bouvier des Flandres, and other non-allergenic dog breeds including large dogs such as the Irish Water Spaniel. These dog breeds are generally considered to be “allergy free dogs” to most people who are allergic to dogs. These Best Hypoallergenic Dogs tend to produce less dander, which is the allergen that causes most sneezing, itching, rashes and other allergic reactions in people with allergies.